Comparison of a New Intranasal Naloxone Formulation to Intramuscular Naloxone: Results from Hypothesis‐generating Small Clinical Studies

Easy‐to‐use naloxone formulations are needed to help address the opioid overdose epidemic. The pharmacokinetics of i.v., i.m., and a new i.n. naloxone formulation (2 mg) were compared in six healthy volunteers. Relative to i.m. naloxone, geometric mean (90% confidence interval [CI]) absolute bioavai...

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Detalles Bibliográficos
Autores principales: Gufford, BT, Ainslie, GR, White, JR, Layton, ME, Padowski, JM, Pollack, GM, Paine, MF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593165/
https://www.ncbi.nlm.nih.gov/pubmed/28504483
http://dx.doi.org/10.1111/cts.12473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593165/
https://www.ncbi.nlm.nih.gov/pubmed/28504483
http://dx.doi.org/10.1111/cts.12473

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