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Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway

Trichostatin A (TSA), a histone deacetylase inhibitor, is widely used as an anticancer drug. Recently, TSA has been shown to exert a protective effect on ischemia/reperfusion (I/R) injury; however, the underlying mechanisms remain unclear. Forkhead box O3a (FoxO3a), a unique FoxO family member, has...

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Detalles Bibliográficos
Autores principales: Guo, Yunhui, Li, Zhiping, Shi, Canxia, Li, Jia, Yao, Meng, Chen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593460/
https://www.ncbi.nlm.nih.gov/pubmed/28849190
http://dx.doi.org/10.3892/ijmm.2017.3101