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Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway
Trichostatin A (TSA), a histone deacetylase inhibitor, is widely used as an anticancer drug. Recently, TSA has been shown to exert a protective effect on ischemia/reperfusion (I/R) injury; however, the underlying mechanisms remain unclear. Forkhead box O3a (FoxO3a), a unique FoxO family member, has...
Autores principales: | Guo, Yunhui, Li, Zhiping, Shi, Canxia, Li, Jia, Yao, Meng, Chen, Xia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593460/ https://www.ncbi.nlm.nih.gov/pubmed/28849190 http://dx.doi.org/10.3892/ijmm.2017.3101 |
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