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Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice

Glucocorticoids (GCs) are known to alter neuronal plasticity, impair learning and memory and play important roles in the generation and progression of Alzheimer's disease. There are no effective drug options for preventing neuronal injury induced by chronic GC exposure. Ginsenoside Rg1 (Rg1) is...

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Detalles Bibliográficos
Autores principales: Zhang, Yaodong, Hu, Wen, Zhang, Biqiong, Yin, Yanyan, Zhang, Junyan, Huang, Dake, Huang, Rongrong, Li, Weiping, Li, Weizu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593467/
https://www.ncbi.nlm.nih.gov/pubmed/28849171
http://dx.doi.org/10.3892/ijmm.2017.3092