Cargando…

Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice

Glucocorticoids (GCs) are known to alter neuronal plasticity, impair learning and memory and play important roles in the generation and progression of Alzheimer's disease. There are no effective drug options for preventing neuronal injury induced by chronic GC exposure. Ginsenoside Rg1 (Rg1) is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yaodong, Hu, Wen, Zhang, Biqiong, Yin, Yanyan, Zhang, Junyan, Huang, Dake, Huang, Rongrong, Li, Weiping, Li, Weizu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593467/ https://www.ncbi.nlm.nih.gov/pubmed/28849171 http://dx.doi.org/10.3892/ijmm.2017.3092

Ejemplares similares

Ginsenoside Rg1 alleviates lipopolysaccharide-induced neuronal damage by inhibiting NLRP1 inflammasomes in HT22 cells
por: Zhang, Yaodong, et al.
Publicado: (2021)

Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage
por: Zhang, Biqiong, et al.
Publicado: (2017)

Ginsenoside Rg1 ameliorates aging-induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice
por: Li, Yan, et al.
Publicado: (2021)

Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice
por: Li, Xuewang, et al.
Publicado: (2022)

Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice
por: Dong, Xianan, et al.
Publicado: (2023)

Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice
por: Zhang, Han, et al.
Publicado: (2021)

Ginsenoside Rg1 alleviates acute liver injury through the induction of autophagy and suppressing NF-κB/NLRP3 inflammasome signaling pathway
por: Zhao, Jinqiu, et al.
Publicado: (2021)

NLRP1 inflammasome involves in learning and memory impairments and neuronal damages during aging process in mice
por: Sun, Dan, et al.
Publicado: (2021)

Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice
por: Ji, Pengmin, et al.
Publicado: (2023)

Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
por: Li, Xuewang, et al.
Publicado: (2023)

Ginsenoside Rg1 protects against H(2)O(2)-induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro
por: Xu, Tan-Zhen, et al.
Publicado: (2019)

Ginsenoside Rg1 Mitigates Porcine Intestinal Tight Junction Disruptions Induced by LPS through the p38 MAPK/NLRP3 Inflammasome Pathway
por: Kang, Jian, et al.
Publicado: (2022)

Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice
por: Han, Yuli, et al.
Publicado: (2022)

Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor-κB pathway and inhibition of inflammasome activation in alcoholic hepatitis
por: Li, Jiajun, et al.
Publicado: (2018)

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy
por: Wang, Ni, et al.
Publicado: (2023)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Effects of Ginsenosides Rg1 on Osteoblasts Cultured with Ti Particles
por: Lin, Yu, et al.
Publicado: (2012)

Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease
por: Liang, Hai-Yong, et al.
Publicado: (2021)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-152
por: Zhang, Rongrong, et al.
Publicado: (2023)

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke
por: Xie, Cheng-long, et al.
Publicado: (2015)

Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS: Rg1 excretion in rat bile, urine and feces
por: He, Chiyu, et al.
Publicado: (2016)

Ginsenosides Rg1 regulate lipid metabolism and temperature adaptation in Caenorhabditis elegans
por: Shi, Hao, et al.
Publicado: (2023)

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
por: LI, HUI, et al.
Publicado: (2014)

A Preclinical Systematic Review of Ginsenoside-Rg1 in Experimental Parkinson's Disease
por: Song, Liang, et al.
Publicado: (2017)

Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats
por: Qin, Qiaoji, et al.
Publicado: (2019)

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1
por: Hsieh, Chao-Chieh, et al.
Publicado: (2023)

Metabolism Study of Notoginsenoside R(1), Ginsenoside Rg(1) and Ginsenoside Rb(1) of Radix Panax Notoginseng in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2011)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells
por: He, Fang, et al.
Publicado: (2020)

Neuroprotective effects of ginsenosides Rh(1 )and Rg(2 )on neuronal cells
por: Li, Xiao-Fan, et al.
Publicado: (2011)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1
por: Liu, Wei, et al.
Publicado: (2021)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
por: Park, Ha-Yan, et al.
Publicado: (2015)

Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis
por: Wang, Tao, et al.
Publicado: (2020)

The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model
por: Hu, Wenxu, et al.
Publicado: (2015)

A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease
por: Li, Naijing, et al.
Publicado: (2016)

Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes
por: Zhang, Ningning, et al.
Publicado: (2022)

The Protective Effect of Ginsenoside Rg1 on Apoptosis in Human Ankle Joint Traumatic Arthritis Chondrocytes
por: Xu, Zhiqiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i1smki04s8mnvmitqq8fbl2ebn