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Role of interferon regulatory factor-1 in lipopolysaccharide-induced mitochondrial damage and oxidative stress responses in macrophages

Sepsis causes many early deaths; both macrophage mitochondrial damage and oxidative stress responses are key factors in its pathogenesis. Although the exact mechanisms responsible for sepsis-induced mitochondrial damage are unknown, the nuclear transcription factor, interferon regulatory factor-1 (I...

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Detalles Bibliográficos
Autores principales: Deng, Song-Yun, Zhang, Le-Meng, Ai, Yu-hang, Pan, Pin-Hua, Zhao, Shuang-Ping, Su, Xiao-Li, Wu, Dong-Dong, Tan, Hong-Yi, Zhang, Li-Na, Tsung, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593470/
https://www.ncbi.nlm.nih.gov/pubmed/28849179
http://dx.doi.org/10.3892/ijmm.2017.3110