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Suppression of CUL4A attenuates TGF-β1-induced epithelial-to-mesenchymal transition in breast cancer cells

Transforming growth factor-β1 (TGF-β1) plays a vital role in the process of epithelial-to-mesenchymal transition (EMT) in breast cancer and the cullin 4A (CUL4A) gene is overexpressed in primary breast cancer. However, whether TGF-β1 signaling can induce CUL4A expression has not been investigated to...

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Detalles Bibliográficos
Autores principales: Wang, Yunshan, Liu, Xiaoyan, Zheng, Hui, Wang, Qin, An, Li, Wei, Guangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593474/
https://www.ncbi.nlm.nih.gov/pubmed/28902348
http://dx.doi.org/10.3892/ijmm.2017.3118