The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning

Neuronal ApoE receptors are linked to learning and memory, but the pathways governing their abundance, and the mechanisms by which they affect the function of neural circuits are incompletely understood. Here we demonstrate that the E3 ubiquitin ligase IDOL determines synaptic ApoER2 protein levels...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Marosi, Mate, Choi, Jinkuk, Achiro, Jennifer M, Kim, Sangmok, Li, Sandy, Otis, Klara, Martin, Kelsey C, Portera-Cailliau, Carlos, Tontonoz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593505/
https://www.ncbi.nlm.nih.gov/pubmed/28891791
http://dx.doi.org/10.7554/eLife.29178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593505/
https://www.ncbi.nlm.nih.gov/pubmed/28891791
http://dx.doi.org/10.7554/eLife.29178

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