Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5′ end of the receptor juxtamembrane domain. On the other...

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Detalles Bibliográficos
Autores principales: Perfetti, Vittorio, Laurini, Erik, Aulić, Suzana, Fermeglia, Maurizio, Riboni, Roberta, Lucioni, Marco, Dallera, Elena, Delfanti, Sara, Pugliese, Luigi, Latteri, Francesco Saverio, Pietrabissa, Andrea, Pricl, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593551/
https://www.ncbi.nlm.nih.gov/pubmed/28915580
http://dx.doi.org/10.18632/oncotarget.19341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593551/
https://www.ncbi.nlm.nih.gov/pubmed/28915580
http://dx.doi.org/10.18632/oncotarget.19341

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