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Time dependent modulation of tumor radiosensitivity by a pan HDAC inhibitor: abexinostat

Despite prominent role of radiotherapy in lung cancer management, there is an urgent need for strategies increasing therapeutic efficacy. Reversible epigenetic changes are promising targets for combination strategies using HDAC inhibitors (HDACi). Here we evaluated on two NSCLC cell lines, the antit...

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Detalles Bibliográficos
Autores principales: Rivera, Sofia, Leteur, Céline, Mégnin, Frédérique, Law, Frédéric, Martins, Isabelle, Kloos, Ioana, Depil, Stéphane, Modjtahedi, Nazanine, Perfettini, Jean Luc, Hennequin, Christophe, Deutsch, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593556/
https://www.ncbi.nlm.nih.gov/pubmed/28915585
http://dx.doi.org/10.18632/oncotarget.14813