Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma

The cell surface receptor CD70 has been previously reported as a promising target for B-cell lymphomas and several solid cancers including renal cell carcinoma. We describe herein the characterization and efficacy of a novel CD70 targeted thorium-227 conjugate (CD70-TTC) comprising the combination o...

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Detalles Bibliográficos
Autores principales: Hagemann, Urs B., Mihaylova, Dessislava, Uran, Steinar R., Borrebaek, Joergen, Grant, Derek, Bjerke, Roger M., Karlsson, Jenny, Cuthbertson, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593563/
https://www.ncbi.nlm.nih.gov/pubmed/28915592
http://dx.doi.org/10.18632/oncotarget.16910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593563/
https://www.ncbi.nlm.nih.gov/pubmed/28915592
http://dx.doi.org/10.18632/oncotarget.16910

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