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Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma

The cell surface receptor CD70 has been previously reported as a promising target for B-cell lymphomas and several solid cancers including renal cell carcinoma. We describe herein the characterization and efficacy of a novel CD70 targeted thorium-227 conjugate (CD70-TTC) comprising the combination o...

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Detalles Bibliográficos
Autores principales:	Hagemann, Urs B., Mihaylova, Dessislava, Uran, Steinar R., Borrebaek, Joergen, Grant, Derek, Bjerke, Roger M., Karlsson, Jenny, Cuthbertson, Alan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593563/ https://www.ncbi.nlm.nih.gov/pubmed/28915592 http://dx.doi.org/10.18632/oncotarget.16910

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