MiR-148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins

Although microRNAs have been recognized as central cellular regulators, there is an evident lack of knowledge about their targets. Here, we analyzed potential target genes for miR-148a functioning in Ras signaling in B cells, including SOS1 and SOS2. A dual-luciferase reporter assay showed significa...

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Detalles Bibliográficos
Autores principales: Alles, Julia, Ludwig, Nicole, Rheinheimer, Stefanie, Leidinger, Petra, Grässer, Friedrich A., Keller, Andreas, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593572/
https://www.ncbi.nlm.nih.gov/pubmed/28915601
http://dx.doi.org/10.18632/oncotarget.17662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593572/
https://www.ncbi.nlm.nih.gov/pubmed/28915601
http://dx.doi.org/10.18632/oncotarget.17662

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