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MiR-148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins
Although microRNAs have been recognized as central cellular regulators, there is an evident lack of knowledge about their targets. Here, we analyzed potential target genes for miR-148a functioning in Ras signaling in B cells, including SOS1 and SOS2. A dual-luciferase reporter assay showed significa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593572/ https://www.ncbi.nlm.nih.gov/pubmed/28915601 http://dx.doi.org/10.18632/oncotarget.17662 |