Metformin increases chemo-sensitivity via gene downregulation encoding DNA replication proteins in 5-Fu resistant colorectal cancer cells

Metformin is most widely prescribed for type 2 diabetes. Recently, evidences have shown that metformin has anticancer effects on pancreatic-, colorectal-, ovarian-, and other cancers. Because metformin has less adverse effects and is inexpensive, it could be a useful chemo-therapeutic agent with ant...

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Detalles Bibliográficos
Autores principales: Kim, Sung-Hee, Kim, Soon-Chan, Ku, Ja-Lok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593582/
https://www.ncbi.nlm.nih.gov/pubmed/28915611
http://dx.doi.org/10.18632/oncotarget.17798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593582/
https://www.ncbi.nlm.nih.gov/pubmed/28915611
http://dx.doi.org/10.18632/oncotarget.17798

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