Cargando…

Alternative promotion and suppression of metastasis by JNK2 governed by its phosphorylation

Fos-related antigen 1 (Fra1) has been proposed as a gatekeeper of the mesenchymal-epithelial transition to epithelial-mesenchymal transition. Here, we showed that de-phosphorylated JNK2 increased the expression of Fra1 by promoting the expression of c-Jun and Jun-B. Conversely, phosphorylated JNK2 s...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Sike, Dong, Xiaoli, Gao, Wenjuan, Stupack, Dwayne, Liu, Yanhua, Xiang, Rong, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593584/
https://www.ncbi.nlm.nih.gov/pubmed/28915613
http://dx.doi.org/10.18632/oncotarget.17507