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PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition

Pre-mRNA processing factor (PRPF) 4B kinase belongs to the CDK-like kinase family, and is involved in pre-mRNA splicing, and in signal transduction. In this study, we observed that PRPF overexpression decreased the intracellular levels of reactive oxygen species, and inhibited resveratrol-induced ap...

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Detalles Bibliográficos
Autores principales: Islam, Salman Ul, Shehzad, Adeeb, Sonn, Jong Kyung, Lee, Young Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593591/
https://www.ncbi.nlm.nih.gov/pubmed/28915620
http://dx.doi.org/10.18632/oncotarget.17855