Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models

Multiple sclerosis (MS) is an autoimmune disease characterized by the dysregulated immune response including innate and adaptive immune responses. Increasing evidence has proven the importance of epigenetic modification in the progression of MS. Recent studies revealed that low-dose decitabine (Dec,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xue, Wang, Jun, Yu, Yong, Ma, Tonghui, Chen, Ping, Zhou, Bing, Tao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593603/
https://www.ncbi.nlm.nih.gov/pubmed/28915632
http://dx.doi.org/10.18632/oncotarget.18063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593603/
https://www.ncbi.nlm.nih.gov/pubmed/28915632
http://dx.doi.org/10.18632/oncotarget.18063

Ejemplares similares