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Marsdenia tenacissima extract overcomes Axl- and Met-mediated erlotinib and gefitinib cross-resistance in non-small cell lung cancer cells

Tyrosine kinase inhibitors (TKIs) are an effective treatment strategy for non-small cell lung cancer (NSCLC) patients harboring mutations that result in constitutive activation of the epidermal growth factor receptor (EGFR). However, most patients eventually develop resistance to TKIs. This occurs d...

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Detalles Bibliográficos
Autores principales: Han, Shu-Yan, Zhao, Wei, Han, Hai-Bo, Sun, Hong, Xue, Dong, Jiao, Yan-Na, He, Xi-Ran, Jiang, Shan-Tong, Li, Ping-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593611/
https://www.ncbi.nlm.nih.gov/pubmed/28915640
http://dx.doi.org/10.18632/oncotarget.18137