Cargando…

Marsdenia tenacissima extract overcomes Axl- and Met-mediated erlotinib and gefitinib cross-resistance in non-small cell lung cancer cells

Tyrosine kinase inhibitors (TKIs) are an effective treatment strategy for non-small cell lung cancer (NSCLC) patients harboring mutations that result in constitutive activation of the epidermal growth factor receptor (EGFR). However, most patients eventually develop resistance to TKIs. This occurs d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Shu-Yan, Zhao, Wei, Han, Hai-Bo, Sun, Hong, Xue, Dong, Jiao, Yan-Na, He, Xi-Ran, Jiang, Shan-Tong, Li, Ping-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593611/ https://www.ncbi.nlm.nih.gov/pubmed/28915640 http://dx.doi.org/10.18632/oncotarget.18137

Ejemplares similares

The Antitumor Activities of Marsdenia tenacissima
por: Wang, Xiang, et al.
Publicado: (2018)

Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells
por: Jiao, Yan-Na, et al.
Publicado: (2018)

Enhancement of gefitinib-induced growth inhibition by Marsdenia tenacissima extract in non-small cell lung cancer cells expressing wild or mutant EGFR
por: Han, Shu-Yan, et al.
Publicado: (2014)

Integrated approach for identifying and evaluating the quality of Marsdenia tenacissima in the medicine market
por: Yu, Ning, et al.
Publicado: (2018)

Nine New Pregnane Glycosides from the Cultivated Medicinal Plant Marsdenia tenacissima
por: Meng, Qian-Qian, et al.
Publicado: (2023)

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer
por: Yi, Ben, et al.
Publicado: (2023)

Studies on the anti-angiogenic effect of Marsdenia tenacissima extract in vitro and in vivo
por: HUANG, ZHENGRONG, et al.
Publicado: (2013)

Total Aglycones from Marsdenia tenacissima Increases Antitumor Efficacy of Paclitaxel in Nude Mice
por: Zhu, Rui-Jing, et al.
Publicado: (2014)

Unigene-based RNA-seq provides insights on drought stress responses in Marsdenia tenacissima
por: Meng, Heng-Ling, et al.
Publicado: (2018)

Marsdenia tenacissima extract suppresses tumor growth and angiogenesis in A20 mouse lymphoma
por: Dai, Xingbin, et al.
Publicado: (2017)

Extract of Marsdenia tenacissima (Roxb.) Moon [Apocynaceae] Suppresses Hepatocellular Carcinoma by Inhibiting Angiogenesis
por: Pan, Yating, et al.
Publicado: (2022)

Nontargeted metabolomics study and pharmacodynamic evaluation of bidirectional fermentation for Ganoderma lucidum with Marsdenia tenacissima
por: Li, Runtian, et al.
Publicado: (2022)

Marsdenia tenacissima Extract Induces Autophagy and Apoptosis of Hepatocellular Cells via MIF/mToR Signaling
por: Lin, Shuai, et al.
Publicado: (2022)

Optimization of Cordyceps sinensis fermentation Marsdenia tenacissima process and the differences of metabolites before and after fermentation
por: Wang, Siqi, et al.
Publicado: (2022)

Polyoxypregnane Glycosides from Root of Marsdenia tenacissima and Inhibited Nitric Oxide Levels in LPS Stimulated RAW 264.7 Cells
por: Na, Zhi, et al.
Publicado: (2023)

Evaluation of Acute and Subacute Oral Toxicity Induced by Ethanolic Extract of Marsdenia tenacissima Leaves in Experimental Rats
por: Porwal, Mayur, et al.
Publicado: (2017)

Oral and injectable Marsdenia tenacissima extract (MTE) as adjuvant therapy to chemotherapy for gastric cancer: a systematic review
por: Zhou, Xu, et al.
Publicado: (2019)

The Protective Effect of Marsdenia tenacissima against Cisplatin-Induced Nephrotoxicity Mediated by Inhibiting Oxidative Stress, Inflammation, and Apoptosis
por: Zhang, Zhiguang, et al.
Publicado: (2023)

C21 Fraction Refined from Marsdenia tenacissima-Induced Apoptosis is Enhanced by Suppression of Autophagy in Human Gastric Cell Lines
por: Li, Kaiqiang, et al.
Publicado: (2020)

Saponins of Marsdenia Tenacissima promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria then activating cytochrome C/Caspase-9/Caspase-3 pathway
por: Jiang, Xiao-pei, et al.
Publicado: (2022)

A Combined Phytochemistry and Network Pharmacology Approach to Reveal Potential Anti-NSCLC Effective Substances and Mechanisms in Marsdenia tenacissima (Roxb.) Moon (Stem)
por: Liu, Pei, et al.
Publicado: (2021)

Overcoming the Intrinsic Gefitinib-resistance via Downregulation of AXL in Non-small Cell Lung Cancer
por: Jeong, Inae, et al.
Publicado: (2019)

Suppression of c-MET overcomes erlotinib resistance in tongue cancer cells
por: Huang, Keqiang, et al.
Publicado: (2018)

Marsdeniae tenacissima extract-induced growth inhibition and apoptosis in hepatoma carcinoma cells is mediated through the p53/nuclear factor-κB signaling pathway
por: Wang, Zhen, et al.
Publicado: (2017)

Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement
por: Wang, Ying, et al.
Publicado: (2016)

Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer
por: Bae, Song Yi, et al.
Publicado: (2015)

Marsdenia tenacissima extract prevents the malignant progression of glioma through upregulating lncRNA MEG3 and SFRP1‐dependent inhibition of Wnt/β‐catenin pathway
por: Chen, Lei, et al.
Publicado: (2023)

C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways
por: Zhang, Yu, et al.
Publicado: (2017)

Predicting Tumor Responses to Gefitinib and Erlotinib
Publicado: (2005)

Efficacy of gefitinib or erlotinib in patients with squamous cell lung cancer
por: Song, Zhengbo, et al.
Publicado: (2013)

AUY922 Effectively Overcomes MET- and AXL-Mediated Resistance to EGFR-TKI in Lung Cancer Cells
por: Choi, Yun Jung, et al.
Publicado: (2015)

Retracted Article: MiR-148a agomir based targeting of c-Met and Her-3 is able to attenuate EGFR-T790M mutation driven gefitinib and erlotinib resistance in non-small cell lung cancer cells
por: Chen, Guimin, et al.
Publicado: (2019)

Correction: Predicting Tumor Responses to Gefitinib and Erlotinib
Publicado: (2012)

Mechanism research of miR‐34a regulates Axl in non‐small‐cell lung cancer with gefitinib‐acquired resistance
por: Xiong, Ran, et al.
Publicado: (2019)

Successful erlotinib rechallenge after both gefitinib- and erlotinib-induced interstitial lung diseases
por: Arakawa, Nobuhito, et al.
Publicado: (2013)

Crizotinib plus erlotinib overcomes osimertinib resistance in a seriously-ill non-small cell lung cancer patient with acquired MET amplification
por: Zhao, Zhi-Mei, et al.
Publicado: (2021)

Shikonin sensitizes wild-type EGFR NSCLC cells to erlotinib and gefitinib therapy
por: Li, Yang-Ling, et al.
Publicado: (2018)

KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
por: Pao, William, et al.
Publicado: (2005)

Case of Proteinuria, Worsening Hypertension, and Glomerular Endotheliosis With Erlotinib and Gefitinib
por: Latcha, Sheron, et al.
Publicado: (2018)

Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study
por: Emery, Ivette F, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ujoddvq4ais7h1jfi0p149f8ha