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Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death

Triple negative breast cancer (TNBC) is a highly metastatic cancer among the breast cancer subgroups. A thorny issue for clinical therapy of TNBC is lack of an efficient targeted therapeutic strategy. We previously created a novel sesquiterpene lactone analog (named DETD-35) derived from plant deoxy...

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Detalles Bibliográficos
Autores principales: Shiau, Jeng-Yuan, Nakagawa-Goto, Kyoko, Lee, Kuo-Hsiung, Shyur, Lie-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593615/
https://www.ncbi.nlm.nih.gov/pubmed/28915644
http://dx.doi.org/10.18632/oncotarget.18183