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Meta-analysis of the incidence and risks of interstitial lung disease and QTc prolongation in non-small-cell lung cancer patients treated with ALK inhibitors

BACKGROUND: To conduct a systematic review and meta-analysis to assess the overall incidence and risk of interstitial lung disease (ILD) and QTc prolongation associated with anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors (-TKIs) in non-small-cell lung cancer (NSCLC) patients. RESULTS: A...

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Detalles Bibliográficos
Autores principales: Lin, Liping, Zhao, Juanjuan, Kong, Ning, He, Yan, Hu, Jiazhu, Huang, Fuxi, Han, Jianjun, Cao, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593649/
https://www.ncbi.nlm.nih.gov/pubmed/28915678
http://dx.doi.org/10.18632/oncotarget.18283