Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice

Adoptive transfer of allogeneic natural killer (NK) cells is an attractive therapy approach against ovarian carcinoma. Here, we evaluated the potency of highly active NK cells derived from human CD34+ haematopoietic stem and progenitor cells (HSPC) to infiltrate and mediate killing of human ovarian...

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Detalles Bibliográficos
Autores principales: Hoogstad-van Evert, Janneke S., Cany, Jeannette, van den Brand, Dirk, Oudenampsen, Manon, Brock, Roland, Torensma, Ruurd, Bekkers, Ruud L., Jansen, Joop H., Massuger, Leon F., Dolstra, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593716/
https://www.ncbi.nlm.nih.gov/pubmed/28919991
http://dx.doi.org/10.1080/2162402X.2017.1320630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593716/
https://www.ncbi.nlm.nih.gov/pubmed/28919991
http://dx.doi.org/10.1080/2162402X.2017.1320630

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