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Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome

Accurate assessment of tumour heterogeneity is an important issue that influences prognosis and therapeutic decision in molecular pathology. Due to the shortage of protective histones and a limited DNA repair capacity, the mitochondrial (mt)-genome undergoes high variability during tumour developmen...

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Detalles Bibliográficos
Autores principales: Amer, Wafa, Toth, Csaba, Vassella, Erik, Meinrath, Jeannine, Koitzsch, Ulrike, Arens, Anne, Huang, Jia, Eischeid, Hannah, Adam, Alexander, Buettner, Reinhard, Scheel, Andreas, Schaefer, Stephan C., Odenthal, Margarete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593826/
https://www.ncbi.nlm.nih.gov/pubmed/28894165
http://dx.doi.org/10.1038/s41598-017-11345-3