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Chronic treatment with Tempol during acquisition or withdrawal from CPP abolishes the expression of cocaine reward and diminishes oxidative damage

In previous studies, we reported that pretreatment with the antioxidant Tempol attenuated the development and expression of cocaine-induced psychomotor sensitization in rats and diminished cocaine-induced oxidative stress (OS) in the prefrontal cortex (PFC) and nucleus accumbens (NAc), suggesting a...

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Detalles Bibliográficos
Autores principales: Beiser, Tehila, Numa, Ran, Kohen, Ron, Yaka, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593848/
https://www.ncbi.nlm.nih.gov/pubmed/28894248
http://dx.doi.org/10.1038/s41598-017-11511-7