Rigidly connected multispecific artificial binders with adjustable geometries

Multivalent binding proteins can gain biological activities beyond what is inherent in the individual binders, by bringing together different target molecules, restricting their conformational flexibility or changing their subcellular localization. In this study, we demonstrate a method to build up...

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Detalles Bibliográficos
Autores principales: Wu, Yufan, Batyuk, Alexander, Honegger, Annemarie, Brandl, Fabian, Mittl, Peer R. E., Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593856/
https://www.ncbi.nlm.nih.gov/pubmed/28894181
http://dx.doi.org/10.1038/s41598-017-11472-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593856/
https://www.ncbi.nlm.nih.gov/pubmed/28894181
http://dx.doi.org/10.1038/s41598-017-11472-x

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