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Optogenetic approach for targeted activation of global calcium transients in differentiated C2C12 myotubes

Excitation-contraction coupling in muscle cells is initiated by a restricted membrane depolarization delimited within the neuromuscular junction. This targeted depolarization triggers an action potential that propagates and induces a global cellular calcium response and a consequent contraction. To...

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Detalles Bibliográficos
Autores principales: Sebille, Stéphane, Ayad, Oualid, Chapotte-Baldacci, Charles-Albert, Cognard, Christian, Bois, Patrick, Chatelier, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593883/
https://www.ncbi.nlm.nih.gov/pubmed/28894267
http://dx.doi.org/10.1038/s41598-017-11551-z