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Optogenetic approach for targeted activation of global calcium transients in differentiated C2C12 myotubes
Excitation-contraction coupling in muscle cells is initiated by a restricted membrane depolarization delimited within the neuromuscular junction. This targeted depolarization triggers an action potential that propagates and induces a global cellular calcium response and a consequent contraction. To...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593883/ https://www.ncbi.nlm.nih.gov/pubmed/28894267 http://dx.doi.org/10.1038/s41598-017-11551-z |