Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation

Hsp104 is a ring-forming protein disaggregase that rescues stress-damaged proteins from an aggregated state. To facilitate protein disaggregation, Hsp104 cooperates with Hsp70 and Hsp40 chaperones (Hsp70/40) to form a bi-chaperone system. How Hsp104 recognizes its substrates, particularly the import...

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Detalles Bibliográficos
Autores principales: Lee, Jungsoon, Sung, Nuri, Mercado, Jonathan M., Hryc, Corey F., Chang, Changsoo, Lee, Sukyeong, Tsai, Francis T. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593927/
https://www.ncbi.nlm.nih.gov/pubmed/28894176
http://dx.doi.org/10.1038/s41598-017-11474-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593927/
https://www.ncbi.nlm.nih.gov/pubmed/28894176
http://dx.doi.org/10.1038/s41598-017-11474-9

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