Positive feedback of the amphiregulin-EGFR-ERK pathway mediates PM2.5 from wood smoke-induced MUC5AC expression in epithelial cells

Biomass fuel smoke is thought to contribute to chronic obstructive pulmonary disease, which is characterized by mucous cell metaplasia and enhanced mucus secretion. We investigated the effect of particulate matter (PM) with a diameter <2.5 μm (PM2.5) from wood smoke (WSPM2.5) on the expression of...

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Detalles Bibliográficos
Autores principales: Huang, Lingmei, Pu, Jinding, He, Fang, Liao, Baoling, Hao, Binwei, Hong, Wei, Ye, Xiuqin, Chen, Jinglong, Zhao, Jun, Liu, Sha, Xu, Juan, Li, Bing, Ran, Pixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593934/
https://www.ncbi.nlm.nih.gov/pubmed/28894207
http://dx.doi.org/10.1038/s41598-017-11541-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593934/
https://www.ncbi.nlm.nih.gov/pubmed/28894207
http://dx.doi.org/10.1038/s41598-017-11541-1

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