N-terminomics identifies widespread endoproteolysis and novel methionine excision in a genome-reduced bacterial pathogen

Proteolytic processing alters protein function. Here we present the first systems-wide analysis of endoproteolysis in the genome-reduced pathogen Mycoplasma hyopneumoniae. 669 N-terminal peptides from 164 proteins were identified, demonstrating that functionally diverse proteins are processed, more...

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Detalles Bibliográficos
Autores principales: Berry, Iain J., Jarocki, Veronica M., Tacchi, Jessica L., Raymond, Benjamin B. A., Widjaja, Michael, Padula, Matthew P., Djordjevic, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593965/
https://www.ncbi.nlm.nih.gov/pubmed/28894154
http://dx.doi.org/10.1038/s41598-017-11296-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593965/
https://www.ncbi.nlm.nih.gov/pubmed/28894154
http://dx.doi.org/10.1038/s41598-017-11296-9

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