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N-terminomics identifies widespread endoproteolysis and novel methionine excision in a genome-reduced bacterial pathogen
Proteolytic processing alters protein function. Here we present the first systems-wide analysis of endoproteolysis in the genome-reduced pathogen Mycoplasma hyopneumoniae. 669 N-terminal peptides from 164 proteins were identified, demonstrating that functionally diverse proteins are processed, more...
Autores principales: | Berry, Iain J., Jarocki, Veronica M., Tacchi, Jessica L., Raymond, Benjamin B. A., Widjaja, Michael, Padula, Matthew P., Djordjevic, Steven P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593965/ https://www.ncbi.nlm.nih.gov/pubmed/28894154 http://dx.doi.org/10.1038/s41598-017-11296-9 |
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