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Prognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature

Growth Factor Independence 1 (GFI1) is a transcriptional repressor that plays a critical role during both myeloid and lymphoid haematopoietic lineage commitment. Several studies have demonstrated the involvement of GFI1 in haematological malignancies and have suggested that low expression of GFI1 is...

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Detalles Bibliográficos
Autores principales: Volpe, Giacomo, Walton, David S., Grainger, David E., Ward, Carl, Cauchy, Pierre, Blakemore, Daniel, Coleman, Daniel J. L., Cockerill, Peter N., Garcia, Paloma, Frampton, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593973/
https://www.ncbi.nlm.nih.gov/pubmed/28894287
http://dx.doi.org/10.1038/s41598-017-11718-8