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Prognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature
Growth Factor Independence 1 (GFI1) is a transcriptional repressor that plays a critical role during both myeloid and lymphoid haematopoietic lineage commitment. Several studies have demonstrated the involvement of GFI1 in haematological malignancies and have suggested that low expression of GFI1 is...
Autores principales: | Volpe, Giacomo, Walton, David S., Grainger, David E., Ward, Carl, Cauchy, Pierre, Blakemore, Daniel, Coleman, Daniel J. L., Cockerill, Peter N., Garcia, Paloma, Frampton, Jon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593973/ https://www.ncbi.nlm.nih.gov/pubmed/28894287 http://dx.doi.org/10.1038/s41598-017-11718-8 |
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