Impact of protein O-GlcNAcylation on neural tube malformation in diabetic embryopathy

Diabetes mellitus in early pregnancy can cause neural tube defects (NTDs) in embryos by perturbing protein activity, causing cellular stress, and increasing programmed cell death (apoptosis) in the tissues required for neurulation. Hyperglycemia augments a branch pathway in glycolysis, the hexosamin...

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Detalles Bibliográficos
Autores principales: Kim, Gyuyoup, Cao, Lixue, Reece, E. Albert, Zhao, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593976/
https://www.ncbi.nlm.nih.gov/pubmed/28894244
http://dx.doi.org/10.1038/s41598-017-11655-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593976/
https://www.ncbi.nlm.nih.gov/pubmed/28894244
http://dx.doi.org/10.1038/s41598-017-11655-6

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