Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance

Disruption of the non-classical Major Histocompatibility Complex (MHC) Ib molecule Qa-1 impairs CD8 Treg and natural killer (NK) cell function and promotes a lupus-like autoimmune disease. This immune perturbation would be expected to enhance anti-transplant responses and impair tolerance induction,...

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Detalles Bibliográficos
Autores principales: Stocks, Blair T., Wilson, Christopher S., Marshall, Andrew F., Brewer, Lauren A., Moore, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593978/
https://www.ncbi.nlm.nih.gov/pubmed/28894277
http://dx.doi.org/10.1038/s41598-017-11780-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593978/
https://www.ncbi.nlm.nih.gov/pubmed/28894277
http://dx.doi.org/10.1038/s41598-017-11780-2

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