The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity

Synthetic cannabinoids and phytocannabinoids have been shown to suppress seizures both in humans and experimental models of epilepsy. However, they generally have a detrimental effect on memory and memory-related processes. Here we compared the effect of the inhibition of the endocannabinoid (eCB) d...

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Detalles Bibliográficos
Autores principales: Colangeli, Roberto, Pierucci, Massimo, Benigno, Arcangelo, Campiani, Giuseppe, Butini, Stefania, Di Giovanni, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593993/
https://www.ncbi.nlm.nih.gov/pubmed/28894217
http://dx.doi.org/10.1038/s41598-017-11606-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593993/
https://www.ncbi.nlm.nih.gov/pubmed/28894217
http://dx.doi.org/10.1038/s41598-017-11606-1

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