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The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity
Synthetic cannabinoids and phytocannabinoids have been shown to suppress seizures both in humans and experimental models of epilepsy. However, they generally have a detrimental effect on memory and memory-related processes. Here we compared the effect of the inhibition of the endocannabinoid (eCB) d...
Autores principales: | Colangeli, Roberto, Pierucci, Massimo, Benigno, Arcangelo, Campiani, Giuseppe, Butini, Stefania, Di Giovanni, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593993/ https://www.ncbi.nlm.nih.gov/pubmed/28894217 http://dx.doi.org/10.1038/s41598-017-11606-1 |
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