Ascorbic acid tethered polymeric nanoparticles enable efficient brain delivery of galantamine: An in vitro-in vivo study

The aim of this work was to enhance the transportation of the galantamine to the brain via ascorbic acid grafted PLGA-b-PEG nanoparticles (NPs) using SVCT2 transporters of choroid plexus. PLGA-b-PEG copolymer was synthesized and characterized by (1)H NMR, gel permeation chromatography, and different...

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Detalles Bibliográficos
Autores principales: Gajbhiye, Kavita R., Gajbhiye, Virendra, Siddiqui, Imtiaz A., Pilla, Srikanth, Soni, Vandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594022/
https://www.ncbi.nlm.nih.gov/pubmed/28894228
http://dx.doi.org/10.1038/s41598-017-11611-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594022/
https://www.ncbi.nlm.nih.gov/pubmed/28894228
http://dx.doi.org/10.1038/s41598-017-11611-4

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