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Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines

Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function...

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Detalles Bibliográficos
Autores principales: Baba, Koichi, Kitajima, Yoshihiko, Miyake, Shuusuke, Nakamura, Jun, Wakiyama, Kota, Sato, Hirofumi, Okuyama, Keiichiro, Kitagawa, Hiroshi, Tanaka, Tomokazu, Hiraki, Masatsugu, Yanagihara, Kazuyoshi, Noshiro, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594024/
https://www.ncbi.nlm.nih.gov/pubmed/28894280
http://dx.doi.org/10.1038/s41598-017-11769-x