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Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo
Seeded propagation of amyloid-beta (Aβ) pathology is suggested to contribute to the progression of Alzheimer’s disease. Local overproduction of aggregation-prone Aβ variants could explain the focal initiation of a seeding cascade that subsequently triggers widespread pathology. Several animal models...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594032/ https://www.ncbi.nlm.nih.gov/pubmed/28894090 http://dx.doi.org/10.1038/s41467-017-00579-4 |