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(1)H, (15)N, (13)C backbone resonance assignments of human phosphoglycerate kinase in a transition state analogue complex with ADP, 3-phosphoglycerate and magnesium trifluoride

Human phosphoglycerate kinase (PGK) is an energy generating glycolytic enzyme that catalyses the transfer of a phosphoryl group from 1,3-bisphosphoglycerate (BPG) to ADP producing 3-phosphoglycerate (3PG) and ATP. PGK is composed of two α/β Rossmann-fold domains linked by a central α-helix and the a...

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Detalles Bibliográficos
Autores principales: Serimbetov, Zhalgas, Baxter, Nicola J., Cliff, Matthew J., Waltho, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594045/
https://www.ncbi.nlm.nih.gov/pubmed/28866776
http://dx.doi.org/10.1007/s12104-017-9758-3