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NMR resonance assignments of the EVH1 domain of neurofibromin’s recruitment factor Spred1

Neurofibromin and Sprouty-related EVH1 domain-containing protein 1 (Spred1) both act as negative regulators of the mitogen-activated protein kinase pathway and are associated with the rare diseases Neurofibromatosis type 1 and Legius syndrome, respectively. Spred1 recruits the major GTPase activatin...

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Detalles Bibliográficos
Autores principales: Führer, Sebastian, Ahammer, Linda, Ausserbichler, Angela, Scheffzek, Klaus, Dunzendorfer-Matt, Theresia, Tollinger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594049/
https://www.ncbi.nlm.nih.gov/pubmed/28831766
http://dx.doi.org/10.1007/s12104-017-9768-1