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Interferon Gamma in African Trypanosome Infections: Friends or Foes?

African trypanosomes cause fatal infections in both humans and livestock. Interferon gamma (IFN-γ) plays an essential role in resistance to African trypanosomes. However, increasing evidence suggests that IFN-γ, when excessively synthesized, also induces immunopathology, enhancing susceptibility to...

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Detalles Bibliográficos
Autores principales: Wu, Hui, Liu, Gongguan, Shi, Meiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594077/
https://www.ncbi.nlm.nih.gov/pubmed/28936213
http://dx.doi.org/10.3389/fimmu.2017.01105