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Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors

Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized class of enzymes known as recombinases facili...

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Detalles Bibliográficos
Autores principales: Kelso, Andrew A., Waldvogel, Sarah M., Luthman, Adam J., Sehorn, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594099/
https://www.ncbi.nlm.nih.gov/pubmed/28936205
http://dx.doi.org/10.3389/fmicb.2017.01716