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Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors
Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized class of enzymes known as recombinases facili...
Autores principales: | Kelso, Andrew A., Waldvogel, Sarah M., Luthman, Adam J., Sehorn, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594099/ https://www.ncbi.nlm.nih.gov/pubmed/28936205 http://dx.doi.org/10.3389/fmicb.2017.01716 |
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