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A unique set of complex chromosomal abnormalities in an infant with myeloid leukemia associated with Down syndrome

BACKGROUND: Children with Down syndrome (DS) have an enhanced risk of developing acute leukemia, with the most common subtype being acute megakaryoblastic leukemia (AMKL). Myeloid leukemia in Down syndrome (ML-DS) is considered a disease with distinct clinical and biological features. There are few...

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Detalles Bibliográficos
Autores principales: de Souza, Daiane Correa, de Figueiredo, Amanda Faria, Ney Garcia, Daniela R., da Costa, Elaine Sobral, Othman, Moneeb A.K., Liehr, Thomas, Abdelhay, Eliana, Silva, Maria Luiza Macedo, de Souza Fernandez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594429/
https://www.ncbi.nlm.nih.gov/pubmed/28912835
http://dx.doi.org/10.1186/s13039-017-0335-3