Cargando…

A unique set of complex chromosomal abnormalities in an infant with myeloid leukemia associated with Down syndrome

BACKGROUND: Children with Down syndrome (DS) have an enhanced risk of developing acute leukemia, with the most common subtype being acute megakaryoblastic leukemia (AMKL). Myeloid leukemia in Down syndrome (ML-DS) is considered a disease with distinct clinical and biological features. There are few...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Souza, Daiane Correa, de Figueiredo, Amanda Faria, Ney Garcia, Daniela R., da Costa, Elaine Sobral, Othman, Moneeb A.K., Liehr, Thomas, Abdelhay, Eliana, Silva, Maria Luiza Macedo, de Souza Fernandez, Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594429/ https://www.ncbi.nlm.nih.gov/pubmed/28912835 http://dx.doi.org/10.1186/s13039-017-0335-3

Ejemplares similares

Molecular cytogenetic studies characterizing a novel complex karyotype with an uncommon 5q22 deletion in childhood acute myeloid leukemia
por: de Figueiredo, Amanda Faria, et al.
Publicado: (2015)

Unbalanced chromosome 1 abnormalities leading to partial trisomy 1q in four infants with Down syndrome and acute megakaryocytic leukemia
por: Silva, Maria Luiza Macedo, et al.
Publicado: (2009)

Cytogenetic as an Important Tool for Diagnosis and Prognosis for Patients with Hypocellular Primary Myelodysplastic Syndrome
por: Corrêa de Souza, Daiane, et al.
Publicado: (2014)

An uncommon t(9;11)(p24;q22) with monoallelic loss of ATM and KMT2A genes in a child with myelodysplastic syndrome/acute myeloid leukemia who evolved from Fanconi anemia
por: Lovatel, Viviane Lamim, et al.
Publicado: (2018)

Do novo del(9)(p13) in a childhood T-cell prolymphocytic leukemia as sole abnormality
por: Wafa, Abdulsamad, et al.
Publicado: (2014)

Patients with chronic myeloid leukemia treated with imatinib who showed the appearance of clonal cytogenetic abnormalities in Philadelphia chromosome-negative cells
por: da Rocha, M M, et al.
Publicado: (2011)

Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia
por: Cofre, Jaime, et al.
Publicado: (2012)

Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: Report of a new case and review of the literature
por: Otero, Luize, et al.
Publicado: (2012)

Influence of aflatoxin B1 on copy number variants in human leukocytes in vitro
por: Harutyunyan, Tigran, et al.
Publicado: (2015)

Hyperdiploidy associated with T315I mutation in BCR-ABL kinase domain in an accelerated phase-chronic myeloid leukemia case
por: Al-Achkar, Walid, et al.
Publicado: (2014)

Acquired del(9)(p22.3) in a primary plasma cell leukemia
por: Achkar, Walid Al, et al.
Publicado: (2013)

Canonical WNT Signaling Pathway is Altered in Mesenchymal Stromal Cells From Acute Myeloid Leukemia Patients And Is Implicated in BMP4 Down-Regulation()
por: Azevedo, Pedro L., et al.
Publicado: (2019)

Piwi like RNA-mediated gene silencing 1 gene as a possible major player in gastric cancer
por: Araújo, Taíssa, et al.
Publicado: (2018)

Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)
por: Alhourani, Eyad, et al.
Publicado: (2014)

Minimally differentiated acute myeloid leukemia with ring/marker derived from chromosome 7 in a child with Down syndrome
por: Borges, Maria Luiza Rocha da Rosa, et al.
Publicado: (2019)

Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development
por: Mencalha, André L, et al.
Publicado: (2014)

Expression Profiles of DNA Methylation and Demethylation Machinery Components in Pediatric Myelodysplastic Syndrome: Clinical Implications
por: Lamim Lovatel, Viviane, et al.
Publicado: (2020)

Aberrant Expression of EZH2 in Pediatric Patients with Myelodysplastic Syndrome: A Potential Biomarker of Leukemic Evolution
por: de Souza Fernandez, Teresa, et al.
Publicado: (2019)

Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
por: Corrêa, Stephany, et al.
Publicado: (2012)

Molecular and Cytogenetic Studies in a Child with Burkitt Lymphoma and Ataxia-Telangiectasia Syndrome Harboring MYC Overexpression and Partial Trisomy 8
por: De Souza, Mariana T., et al.
Publicado: (2018)

Down syndrome associated childhood myeloid leukemia with yet unreported acquired chromosomal abnormalities and a new potential adverse marker: dup(1)(q25q44)
por: Moassass, Faten, et al.
Publicado: (2018)

High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia
por: Othman, Moneeb A. K., et al.
Publicado: (2015)

Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia
por: Mencalha, André L, et al.
Publicado: (2014)

An unusual T-cell childhood acute lymphoblastic leukemia harboring a yet unreported near-tetraploid karyotype
por: Garcia, Daniela RN, et al.
Publicado: (2011)

Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands
por: Thielker, Jovanna, et al.
Publicado: (2020)

An adult B-cell precursor acute lymphoblastic leukemia with multiple secondary cytogenetic aberrations
por: AL-Achkar, Walid, et al.
Publicado: (2014)

A de novo acute myeloid leukemia (AML-M4) case with a complex karyotype and yet unreported breakpoints
por: Al-achkar, Walid, et al.
Publicado: (2013)

Learning by exclusion in individuals with autism and Down syndrome
por: Langsdorff, Luiza Costa, et al.
Publicado: (2017)

Transient abnormal myelopoiesis with pericardial effusion in Down syndrome: Case report
por: Falasco, Bianca Francisco, et al.
Publicado: (2019)

A Novel Constitutional t(3;8)(p26;q21) and ANKRD26 and SRP72 Variants in a Child with Myelodysplastic Neoplasm: Clinical Implications
por: Lovatel, Viviane Lamim, et al.
Publicado: (2023)

HNF4A expression as a potential diagnostic tool to discriminate primary gastric cancer from breast cancer metastasis in a Brazilian cohort
por: Jucá, Patrícia Chaves de Freitas Campos, et al.
Publicado: (2017)

Molecular characterization of the rare translocation t(3;10)(q26;q21) in an acute myeloid leukemia patient
por: Jancuskova, Tereza, et al.
Publicado: (2014)

The Mutational Landscape of Myeloid Leukaemia in Down Syndrome
por: de Castro, Carini Picardi Morais, et al.
Publicado: (2021)

A novel dic (17;18) (p13.1;q11.2) with loss of TP53 and BCR/ABL rearrangement in an Imatinib resistant chronic myeloid leukemia
por: Al-achkar, Walid, et al.
Publicado: (2012)

Misdiagnosis of ventricular tachycardia is not unique to emergency physicians()
por: deSouza, Ian S.
Publicado: (2023)

Age and cytogenetic abnormalities()
por: Souza, Cármino Antonio de
Publicado: (2018)

New Therapeutic Strategies for Obesity and Its Metabolic Sequelae: Brazilian Cerrado as a Unique Biome
por: Monteiro-Alfredo, Tamaeh, et al.
Publicado: (2023)

Berkeley problems in mathematics /
por: De Souza, Paulo Ney
Publicado: (2004)

A new adult AML case with an extremely complex karyotype, remission and relapse combined with high hyperdiploidy of a normal chromosome set in secondary AML
por: Wafa, Abdulsamad, et al.
Publicado: (2018)

The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia
por: Nestal de Moraes, Gabriela, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_g06s5iav99nirg1gnibn9s4aeh