Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells

[Image: see text] The emergence of Mycobacterium tuberculosis (MTB) strains that are resistant to most or all available antibiotics has created a severe problem for treating tuberculosis and has spurred a quest for new antibiotic targets. Here, we demonstrate that trans-translation is essential for...

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Detalles Bibliográficos
Autores principales: Alumasa, John N., Manzanillo, Paolo S., Peterson, Nicholas D., Lundrigan, Tricia, Baughn, Anthony D., Cox, Jeffery S., Keiler, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594445/
https://www.ncbi.nlm.nih.gov/pubmed/28762275
http://dx.doi.org/10.1021/acsinfecdis.7b00028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594445/
https://www.ncbi.nlm.nih.gov/pubmed/28762275
http://dx.doi.org/10.1021/acsinfecdis.7b00028

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