Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

BACKGROUND: Pancreatic cancer is generally acknowledged as the most common primary malignant tumor, and it is known to be resistant to conventional chemotherapy. Novel, selective antitumor agents are pressingly needed. METHODS: CCK-8 and colony formation assay were used to investigate the cell growt...

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Detalles Bibliográficos
Autores principales: Xu, Zihang, Zhang, Fei, Bai, Chao, Yao, Chao, Zhong, Hairong, Zou, Chunpu, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594456/
https://www.ncbi.nlm.nih.gov/pubmed/28893319
http://dx.doi.org/10.1186/s13046-017-0590-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594456/
https://www.ncbi.nlm.nih.gov/pubmed/28893319
http://dx.doi.org/10.1186/s13046-017-0590-5

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